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you will need to navigate to your PlayOnLinux directory which should be something like /usr/share/playonlinux/

in /usr/share/playonlinux/lib is where you will find the first file you need to edit called sources and comment them out by putting a # in front of these lines

Source code

if [ "$(id -u)" = "0" ]
then
echo "PlayOnLinux is not supposed to be run as root. Sorry"
exit
fi

then edit /usr/share/playonlinux/python/mainwindow.­py and comment these lines

Source code

if(os.popen("id -u").read() == "0\n" or os.popen("id -u").read() == "0"):
wx.MessageBox(_("{0} is not supposed to be run as root. Sorry").format(os.environ["APP­LICATION_TITLE"]),_("Error&quo­t;))
os._exit(0)

To uninstall PlayOnLinux you need to run below given commands. :

Source code

sudo apt-get install ppa-purge
sudo ppa-purge ppa:ubuntu-wine/ppa